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What Does Spravato Do?

What Does Spravato Do?

Finding an effective treatment for depression can be frustrating and time-consuming. While there are many treatment options currently available, choosing one that works for you can require extensive trial and error as you sort through bothersome side effects, high costs, or lack of results. 

Spravato is an advanced treatment that offers a path forward. Designed specifically for individuals with depression who have not responded to traditional treatments, this advanced therapy can provide rapid relief that lasts. Many who have heard of this treatment wonder, “What does Spravato do?” Our compassionate team at Upswing Psychiatry is here to help you understand how this innovative nasal spray works and what to expect from your healing journey. 

What Is Spravato? 

Spravato is a cutting-edge therapy for people suffering from treatment-resistant depression (TRD) or major depressive disorder (MDD). It is administered as a nasal spray and contains esketamine, a compound known for its fast-acting effects. Spravato is particularly helpful for patients dealing with acute depressive symptoms or suicidal thoughts, especially when standard antidepressants have not been effective. 

All treatments are conducted in our office under the careful supervision of one of our board-certified providers, who will closely monitor your mental and physical well-being to ensure the treatment is both safe and effective.

The Science Behind Spravato

Spravato takes a different route than traditional antidepressants by acting on the brain’s NMDA (glutamate) receptors to balance neurotransmitters involved in mood and cognitive function. Additionally, it enhances neuroplasticity—your brain’s natural ability to rebuild and strengthen connections that may have been disrupted by prolonged depression.

While oral antidepressants work well for some, up to one-third of patients see little to no improvement, and many deal with unwanted side effects. Current research shows that 88 percent of patients using Spravato reported notable symptom relief within just 24 hours.

Are You a Candidate? 

As the only esketamine-based nasal spray currently approved by the FDA, Spravato is considered safe and generally well tolerated. Because of this, it is a good option for many people seeking relief from depression. As Spravato is designed for people with TRD, good candidates for this treatment will already have tried two or more different antidepressants without success. This is often a prerequisite for insurance providers to cover Spravato. 

Spravato can cause a temporary increase in blood pressure. Ideal candidates will also not have any uncontrolled medical conditions such as hypertension, aneurysms, certain heart problems, or a history of brain bleeds. While our clinicians will carefully monitor you during treatment, this medication is not recommended for people with such conditions. Individuals with a history of substance use disorders may also require careful evaluation before determining eligibility for treatment. 

The best way to know if you are a candidate for Spravato is to schedule an initial consultation with our team. One of our board-certified providers will explain what Spravato does and ask you questions about your medical and psychiatric history, current health status, and treatment goals. We will then be able to determine your eligibility and create a customized treatment plan that addresses your unique needs. 

Contact Us Today To Find Out What Spravato Does and Whether It Is Right for You 

Spravato is gaining popularity for its ability to offer substantial and long-awaited relief for people struggling with depression. For many, it provides a renewed sense of hope and a foundation for improved well-being. 

If you are wondering, “What does Spravato do?” our team is here to answer your questions and ensure your comfort throughout the treatment process. At Upswing Psychiatry, we are experts in the field of advanced mental health care and are excited to support you on your journey toward wellness. Contact us today to get started with Spravato.