When multiple medications have failed in treating your depression, you may feel you have exhausted your options. At Upswing Psychiatry, we recognize the emotional toll and frustration that major depressive disorder (MDD) and treatment-resistant depression (TRD) can cause. As one of the nation’s busiest single-center practices, we remain committed to delivering advanced, evidence-based treatments that offer meaningful relief. Call today to schedule an appointment and learn who can benefit from Spravato treatment in Amarillo.
Spravato (esketamine) is an FDA-approved nasal spray used to treat adults with MDD and TRD who have tried at least two oral antidepressants without adequate improvement. The FDA has also approved Spravato for individuals diagnosed with MDD accompanied by suicidal ideation or behavior. Spravato treatment rapidly alleviates depressive symptoms and suicidal thoughts, delivering results to those who have not benefited from traditional medications available in Amarillo.
Unlike conventional antidepressants that target serotonin, Spravato acts on NMDA receptors in the brain, helping to restore healthy communication between nerve cells. This treatment typically works more quickly than traditional medications, with some patients noticing improvements within just 24 to 48 hours of their first Spravato treatment session.
Spravato acts as an NMDA receptor antagonist, targeting glutamate, a key chemical messenger in the brain involved in mood regulation. Although researchers have not fully defined glutamate’s role in depression, its influence appears significant in treatment-resistant cases.
Treatment begins with an induction phase lasting 14 treatment rounds. During the first four weeks, you will receive two treatments per week. In the next four weeks, the frequency of treatment decreases to once per week, while during the final four weeks of the induction phase, you will receive one treatment every other week. This gradual tapering allows us to monitor your response and determine the most appropriate long-term maintenance plan.
Once you complete the introduction phase, you will transition into continuation and maintenance therapy. We tailor this phase to fit your individual progress. While some patients benefit from weekly treatments, others require less frequent sessions. Our goal is to help you maintain symptom relief while minimizing unnecessary interventions.
You will self-administer the nasal spray under close medical supervision at our clinic. After each session, our Amarillo providers will monitor you for approximately two hours to observe any side effects, ensure your safety, and optimize Spravato’s benefits. Because the medication may impair alertness, a trusted friend or family member must drive you home following each treatment session.
If you are living with major depressive disorder that has not responded to traditional antidepressants, you may benefit from Spravato therapy at our Amarillo clinic. This FDA-approved treatment provides a novel approach for individuals diagnosed with TRD or MDD accompanied by suicidal ideation.
Spravato delivers rapid relief, reduces suicidal thoughts, and supports sustained improvement in depressive symptoms. You may begin noticing changes within days—far sooner than the typical response time for standard medications. In addition, clinical studies show that Spravato can quickly ease suicidal ideation, helping you feel more emotionally stable.
With continued therapy and personalized maintenance plans, many patients experience lasting relief from symptoms of depression. Our team customizes each treatment to meet your specific needs, ensuring consistent support throughout your care. Please note that Spravato is not approved for anxiety disorders and is specifically indicated for patients diagnosed with TRD or depression involving suicidal thoughts or behaviors.
At Upswing Psychiatry, we customize your every treatment to your unique needs. Our experienced providers take time to understand your medical history, previous therapies, and wellness goals. From your initial consultation through each Spravato session, we offer compassionate care and individualized support that reflects our commitment to your well-being.
If traditional antidepressants have not eased your symptoms of major depression, Spravato may offer the breakthrough you have been seeking. Contact us today to schedule your consultation and find out who can benefit from Spravato treatment in Amarillo.